发明名称 NEW PLC-LIKE PROTEIN AND UTILIZATION OF THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide a new PLC (phospholipase C)-like protein playing an important role in a living body, a gene encoding the same, the use of the protein or gene as a medicine and a method for screening a compound regulating the expression of the protein and gene. <P>SOLUTION: This new PLC-like protein is obtained from polynucleotides described in any of (a) a polynucleotide encoding a protein having a specific amino acid sequence, (b) a polynucleotide containing a coding region of a specific base sequence, (c) a polynucleotide containing a base sequence encoding a protein consisting of an amino acid sequence obtained by substituting, deleting, inserting and/or adding one or a multiple number of amino acids in the specific amino acid sequence and having a PLC activity, and (d) a polynucleotide hybridizing with a DNA consisting of the specific base sequence, under a stringent condition and having the PLC activity. <P>COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006180738(A) 申请公布日期 2006.07.13
申请号 JP20040375846 申请日期 2004.12.27
申请人 TOKYO UNIV OF PHARMACY & LIFE SCIENCE 发明人 FUKAMI KIYOKO;NAKAHARA MASAMICHI;NAKAMURA YOSHIKAZU
分类号 C12N15/09;A61K35/76;A61K38/00;A61P25/00;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/16;C12Q1/02;G01N33/15;G01N33/50 主分类号 C12N15/09
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