发明名称 |
TARGETED CHIMERIC MOLECULES FOR CANCER THERAPY |
摘要 |
The present invention concerns chimeric cancer therapeutic molecules comprising a targeting moiety and an anti-cell proliferation moiety. The anti-cell proliferation moiety may comprise a cytotoxic agent or an apoptosis-inducing factor, in specific embodiments. In particular embodiments, the anti-cell proliferation mechanism of the chimeric molecules comprises apoptotic pathways. In additional embodiments, the chimeric molecules of the present invention provide sensitivity to chemotherapy in a cell that is resistant to the chemotherapy. |
申请公布号 |
WO2006074451(A2) |
申请公布日期 |
2006.07.13 |
申请号 |
WO2006US00828 |
申请日期 |
2006.01.10 |
申请人 |
RESEARCH DEVELOPMENT FOUNDATION;ROSENBLUM, MICHAEL, G.;ELLINGTON, ANDREW, D. |
发明人 |
ROSENBLUM, MICHAEL, G.;ELLINGTON, ANDREW, D. |
分类号 |
A61K47/48;A61P35/00;C07K14/525;C07K16/28;C07K16/30;C07K16/32;C07K19/00;C12N9/64 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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