发明名称 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF OBESITY AND SEXUAL DYSFUNCTION |
摘要 |
The present invention relates to methods of treating and preventing obesity and obesity-related disorders in a subject comprising administering a neurokinin-1 antagonist and an anti-obesity agent, such as a melanocortin 4 receptor agonist, to said subject. The present invention further relates to methods of treating or preventing sexual dysfunction, including male erectile dysfunction, in a subject comprising administering a neurokinin-1 antagonist and a sexual dysfunction therapeutic agent, such as a melanocortin 4 receptor agonist, to said subject. The present invention further provides for pharmaceutical compositions and medicaments useful in carrying out these methods.
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申请公布号 |
WO2006049933(A3) |
申请公布日期 |
2006.07.13 |
申请号 |
WO2005US38194 |
申请日期 |
2005.10.25 |
申请人 |
MERCK & CO., INC.;MACCOSS, MALCOLM;MACINTYRE, DUNCAN, E.;STRACK, ALISON, M. |
发明人 |
MACCOSS, MALCOLM;MACINTYRE, DUNCAN, E.;STRACK, ALISON, M. |
分类号 |
A61K38/00;A61K31/135;A61K31/235;A61K31/24;A61K31/445;A61K31/535;A61K31/675 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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