METHODS OF DETERMINING PRECISE HERG INTERACTIONS BY MUTAGENESIS
摘要
The present invention discloses methods of determining highly precise interactions between the HERG ion channel and various compounds. The methods of the present invention utilize modified HERG ion channels combined with heterologous in vivo expression in Xenopus oocytes and mammalian cells.
申请公布号
WO2006039716(A3)
申请公布日期
2006.07.13
申请号
WO2005US35870
申请日期
2005.10.03
申请人
NEURION PHARMACEUTICALS, INC.;DOUGHERTY, DENNIS, A.;LESTER, HENRY, A.;NOWAK, MARK, W.
发明人
DOUGHERTY, DENNIS, A.;LESTER, HENRY, A.;NOWAK, MARK, W.
