BETA ADRENERGIC DRUG CONJUGATED TO BONE TARGETING MOIETY FOR MODULATING BONE MASS

摘要

The instant invention relates to compositions and methods for treating or preventing bone diseases. In certain aspects, the invention provides compositions comprising a ß-adrenergic antagonist or agonist associated to a bone-targeted molecule, as well as methods of modulating bone mass and/or growth in a mammal by administering a composition of the present invention. In other aspects, the invention provides methods of modulating bone mass and/or growth in a mammal by administering a composition comprising a ß2-selective antagonist or agonist.