| 摘要 |
<p>The present invention concerns a controlled release dosage form comprising (I) a tetracycline, (II) an excipient selected from waxes, fats or glycerides or other esters of fatty acids with polyols and (III) a cellulose or acrylate polymer or polyvinyl - pyrrolidone; (II) is present in a range of 8.35% of (I) and (III) is present in the range of 20 - 100% of (I). Preferred is a capsule containing pellets of minocycline, glycerol monostearate, cellulose and polyvinyl pyrrolidone.</p> |
