发明名称 |
SCANNING KELVIN MICROPROBE SYSTEM AND PROCESS FOR ANALYZING A SURFACE |
摘要 |
<p>There is provided a system and process for detecting biomolecular interaction on a substrate having a biomolecule immobilized on a surface of the substrate. The system and process incorporate a scanning Kelvin microprobe (SKM) capable of analyzing surface topography as well as a contact potential difference image signal. Also provided is the use of SKM in measuring and analyzing biochemical molecular interactions between a probe bound to the surface of the substrate, and a target suspected to be present in a liquid sample. One of the probe and target combination is a biomolecule such as a nucleic acid, a polypeptide, or a small molecule, and an antibody antigen combination may be used.</p> |
申请公布号 |
EP1295119(B1) |
申请公布日期 |
2006.07.12 |
申请号 |
EP20010935857 |
申请日期 |
2001.05.18 |
申请人 |
SENSORCHEM INTERNATIONAL CORPORATION |
发明人 |
THOMPSON, MICHAEL;CHERAN, LARISA-EMILIA |
分类号 |
G01N33/483;G01N27/00;G01N33/543;G01Q60/30 |
主分类号 |
G01N33/483 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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