发明名称 HETEROARYL COUMARINS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS
摘要 Compounds having the formula I: (see formula I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.</SDOAB >
申请公布号 CA2125824(C) 申请公布日期 2006.07.11
申请号 CA19942125824 申请日期 1994.06.14
申请人 MERCK FROSST CANADA INC. 发明人 FORTIN, REJEAN;GIRARD, YVES;GRIMM, ERICH;HUTCHINSON, JOHN;SCHEIGETZ, JOHN
分类号 C07D493/08;A61K31/37;A61K45/06;C07D311/16;C07D407/12;C07D407/14;C07D409/14;C07D411/12;C07D413/14;C07D417/14;C07D471/04;C07D491/048;C07D495/04 主分类号 C07D493/08
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