发明名称 Kinase inhibitors
摘要 The invention relates to inhibitors of enzymes that bind to ATP or GTP and/or catalyze phosphoryl transfer, compositions comprising the inhibitors, and methods of using the inhibitors and inhibitor compositions. The inhibitors and compositions comprising them are useful for treating disease or disease symptoms. The invention also provides for methods of making phosphoryl transferase inhibitor compounds, methods of inhibiting phosphoryl transferase activity, and methods for treating disease or disease symptoms.
申请公布号 US7074789(B2) 申请公布日期 2006.07.11
申请号 US20030699518 申请日期 2003.10.31
申请人 AMGEN INC. 发明人 ARMISTEAD DAVID M.;BEMIS JEAN E.;BUCHANAN JOHN L.;DIPIETRO LUCIAN V.;ELBAUM DANIEL;GEUNS-MEYER STEPHANIE D.;HABGOOD GREGORY J.;KIM JOSEPH L.;MARSHALL TERESA L.;NOVAK PERRY M.;NUNES JOSEPH J.;PATEL VINOD F.;TOLEDO-SHERMAN LETICIA M.;ZHU XIAOTIAN
分类号 C07D251/16;C07D403/12;A61K31/4155;A61K31/53;A61K31/5377;A61K45/00;A61P9/00;A61P35/04;A61P43/00;C07D251/18;C07D251/22;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/14;C07D405/04;C07D405/14;C07D407/14;C07D409/04;C07D409/12;C07D409/14;C07D413/04;C07D413/12;C07D413/14;C07D417/04;C07D417/12;C07D417/14;C07D471/04 主分类号 C07D251/16
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