发明名称 |
Nucleozymes |
摘要 |
Nucleozymes containing ribonucleotides and deoxyribonucleotides or nucleic acid analogues are described herein. The nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme counterparts. Also described are methods for preparing the nucleozymes along with methods of using nucleozymes, e.g., as therapeutic agents.
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申请公布号 |
US7074601(B2) |
申请公布日期 |
2006.07.11 |
申请号 |
US20020102094 |
申请日期 |
2002.03.19 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
USMAN NASSIM;CEDERGREN ROBERT J;PERREAULT JEAN-PIERRE;YANG JING-HUA;RICH ALEXANDER |
分类号 |
C12N9/00;C12P19/34;A61K31/70;A61K38/00;A61K48/00;A61P31/18;C07H21/04;C12N15/113 |
主分类号 |
C12N9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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