PROCESS

摘要

A process producing a pharmaceutical lozenge formulation comprising the step s of: 1) granulating a mixture of flurbiprofen and a bulking agent with a solution of a binding agent in a polar solvent to form granules; 2) melting a lozenge-forming composition; 3) mixing the granules with the molten lozenge-forming composition; 4) forcing the resulting mixture into lozenges each containing a therapeutically effective amount of flurbiprofen.