| 发明名称 |
ARIPIPRAZOLE MEDICINAL AGENT OF LOW HYGROSCOPICITY AND METHODS FOR ITS PREPARING |
| 摘要 |
FIELD: pharmacy. ^ SUBSTANCE: invention relates to the improved formulation of aripiprazole showing the reduced hygroscopicity. These formulations are not converted to hydrate and not loss the initial solubility being even the medicinal preparation comprising anhydrous apipiprazole crystals are stored for a long time. Also, invention describes method for preparing these formulation and pharmaceutical composition based on thereof. ^ EFFECT: improved and valuable pharmaceutical properties of agent. ^ 22 cl, 32 dwg, 7 tbl, 28 ex |
| 申请公布号 |
RU2279429(C2) |
申请公布日期 |
2006.07.10 |
| 申请号 |
RU20040126636 |
申请日期 |
2002.09.25 |
| 申请人 |
|
发明人 |
BANDO TAKUDZI;AOKI SATOSI;KAVASAKI DZUNITI;ISIGAMI MAKOTO;TANIGUTI JOUITI;JABUUTI TSUJOSI;FUDZIMOTO KIJOSI;NISIOKA JOSIKHIRO;KOBAJASI NORIJUKI;FUDZIMURA TSUTOMU;TAKAKHASI MASANORI;ABE KAORU;NAKAGAVA TOMONORI;SINKHAMA KOITI;UTSUMI NAOTO;TOMINAGA MITIAKI;OI JOSIKHIRO;JAMADA SOKHEI;TOMIKAVA KENDZI |
| 分类号 |
C07D215/22;C07D401/12;A61K;A61K9/14;A61K9/16;A61K9/20;A61K31/4704;A61K31/496;A61K31/501;A61P;A61P1/08;A61P3/04;A61P15/10;A61P25/00;A61P25/04;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/32;B01D9/02;C07D;C07D215/227 |
主分类号 |
C07D215/22 |
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