Fremgangsmåde til adskillelse af rotavirus-varianter samt levende, svækket rotavirus-vaccine
摘要
The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly provides a rotavirus population designated as P43. The invention further provides a novel formulation for a rotavirus vaccine which is in the form of a quick dissolving tablet for immediate dissolution when placed on the tongue.
申请公布号
DK1212084(T3)
申请公布日期
2006.07.10
申请号
DK20000958452T
申请日期
2000.08.15
申请人
GLAXOSMITHKLINE BIOLOGICALS S.A.
发明人
COLAU, BRIGITTE, DESIREE, A.;DENAMUR, FRANCOISE;KNOTT, ISABELLE;POLISZCZAK, ANNICK;VANDE VELDE, VINCENT;THIRY, GEORGES