发明名称 ПРОИЗВОДНЫЕ НАФТИЛЕНА КАК ИНГИБИТОРЫ ЦИТОХРОМА Р450
摘要 Compounds of the formula (I); and pharmaceutically acceptable salts thereof, wherein n1, n2, n3, n4, G <1>,Q<1>, Z, R<1>, R<2>, R<3>, R<4a>, R<4b>, R<5a>, and R<5b> are defined herein, inhibit the cytochrome P450RAI enzyme and are useful for the treatment and/or prevention of various diseases and conditions which respond to treatment by retinoids and by naturally occurring retinoic acid.
申请公布号 RU2006103996(A) 申请公布日期 2006.07.10
申请号 RU20060103996 申请日期 2004.07.12
申请人 ОСИ ФАРМАСЬЮТИКАЛЗ, ИНК. (US) 发明人 СМИТ Ванесса (GB);НАЙГРО Энтони (US);МАЛВИХИЛЛ Марк (US);СЕСАРИО Кара (US);БЕК Патриши  Энн (US);КАСТЭЛАНО Арлиндо Лукас (US)
分类号 C07D233/24;A61P35/00;C07D233/54;C07D249/04 主分类号 C07D233/24
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