发明名称 Integrin targeted imaging agents
摘要 Emulsions preferably of nanoparticles formed from high boiling liquid perfluorochemical substances, said particles coated with a lipid/surfactant coating are made specific to regions of activated endothelial cells by coupling said nanoparticles to a ligand specific for alpha<SUB>v</SUB>beta<SUB>3 </SUB>integrin, other than an antibody. The nanoparticles may further include biologically active agents, radionuclides, or other imaging agents.
申请公布号 US2006147380(A1) 申请公布日期 2006.07.06
申请号 US20050305416 申请日期 2005.12.16
申请人 发明人 LANZA GREGORY M.;WICKLINE SAMUEL A.;HARRIS TOM
分类号 A61K38/04;A61K31/4709;A61K31/4745;A61K47/22;A61K47/42;A61K47/48;A61K49/00;A61K49/10;A61K49/18 主分类号 A61K38/04
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