摘要 |
Emulsions preferably of nanoparticles formed from high boiling liquid perfluorochemical substances, said particles coated with a lipid/surfactant coating are made specific to regions of activated endothelial cells by coupling said nanoparticles to a ligand specific for alpha<SUB>v</SUB>beta<SUB>3 </SUB>integrin, other than an antibody. The nanoparticles may further include biologically active agents, radionuclides, or other imaging agents.
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