发明名称 |
Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them |
摘要 |
The present invention relates to the novel isoindolone derivatives of the formula I in which R1 to R6 have the meanings stated in the claims. The inventive compounds are suitable as antiarrhythmic medicaments with a cardioprotective component for infarction prophylaxis and infarction treatment and for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiological processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure.
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申请公布号 |
US2006148880(A1) |
申请公布日期 |
2006.07.06 |
申请号 |
US20060365319 |
申请日期 |
2006.03.01 |
申请人 |
AVENTIS PHARMA S.A. |
发明人 |
KLEEMANN HEINZ-WERNER;HOFMEISTER ARMIN;CARRY JEAN-CHRISTOPHE;RONAN BAPTISTE;MIGNANI SERGE;BIGOT ANTONY |
分类号 |
A61K31/4035;C07D209/46;C07D403/02 |
主分类号 |
A61K31/4035 |
代理机构 |
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地址 |
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