发明名称 |
TARGETING VIRUSES USING A MODIFIED SINDBIS GLYCOPROTEIN |
摘要 |
The present invention relates to viruses that are engineered to contain a surface ligand molecule which targets the virus to a cell of interest. In particular non-limiting embodiments, the cell of interest is desirably ablated and may be a cancer cell, an infected cell, a cell exhibiting a non-malignant proliferative disorder, or a cell of the immune system. Alternatively, the cell of interest is a target for gene therapy.
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申请公布号 |
WO2006031996(A3) |
申请公布日期 |
2006.07.06 |
申请号 |
WO2005US33062 |
申请日期 |
2005.09.14 |
申请人 |
M OF HIGHER EDUCATION UNIVERSITY OF PITTSBURGH OFTHE COMMONWEALTH SYSTE;BERGMAN, IRA;WHITAKER-DOWLING, PATRICIA |
发明人 |
BERGMAN, IRA;WHITAKER-DOWLING, PATRICIA |
分类号 |
C12N15/09;A61K38/00;C07K16/00;C07K16/28;C07K16/30;C07K16/32;C12N7/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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