| 发明名称 |
VERFAHREN ZUR HEMMUNG DER EXPRESSION EINE ZIELGENS |
| 摘要 |
<p>Inhibiting expression of a target gene (I) in a cell by introducing an inhibitory RNA (dsRNA1) having a double-stranded structure of at most 49 consecutive bases, is new. At least part of one strand (as1) of dsRNA1 is complementary to (I) and at least one end of dsRNA1 has an overhang of 1-4 nucleotides (nt).</p> |
| 申请公布号 |
DE50206993(D1) |
申请公布日期 |
2006.07.06 |
| 申请号 |
DE2002506993 |
申请日期 |
2002.01.09 |
| 申请人 |
ALNYLAM EUROPE AG |
发明人 |
KREUTZER, ROLAND;LIMMER, STEPHAN;LIMMER, SYLVIA;HADWIGER, PHILIPP |
| 分类号 |
C12N15/09;A61K9/127;A61K31/7105;A61K31/7115;A61K31/7125;A61K31/713;A61K38/00;A61K47/34;A61K47/48;A61K48/00;A61P5/00;A61P9/00;A61P25/28;A61P31/12;A61P33/06;A61P35/00;A61P35/04;A61P37/02;A61P43/00;C07H21/02;C12N15/11;C12N15/113;C12N15/88 |
主分类号 |
C12N15/09 |
| 代理机构 |
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代理人 |
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