METHODS TO TRIGGER, MAINTAIN AND MANIPULATE IMMUNE RESPONSES BY TARGETED ADMINISTRATION OF BIOLOGICAL RESPONSE MODIFIERS INTO LYMPHOID ORGANS
摘要
The present invention includes use of a biological response modifier (BRM) to modulate an immune response in a subject while avoiding or limiting common side-effects associate with BRM use. The BRMs of the present invention can be injected into a secondary lymphatic organ of the subject or into an area of relatively high drainage into a secondary lymphatic organ of the subject. The modulated immune response can be general or antigen-specific.
申请公布号
WO2006071934(A2)
申请公布日期
2006.07.06
申请号
WO2005US47250
申请日期
2005.12.29
申请人
MANNKIND CORPORATION;KUNDIG, THOMAS;BOT, ADIRAN, ION