| 摘要 |
PROBLEM TO BE SOLVED: To provide a new method for synthesizing a compound having a pharmacological activity. SOLUTION: This method for producing methyl 3-chloro-3H-indole-3-carboxylate includes reacting a proper 3-carboxylate indole compound with N-chlorosuccinimide in the presence of a tertiary amine having a lower nucleophilicity than that of DABCO (1,4-diazabicyclo[2.2.2]octane) and having a pK<SB>b</SB>of 8 to 11. COPYRIGHT: (C)2006,JPO&NCIPI
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