发明名称 |
Purified composition of bispecific molecules and methods of production |
摘要 |
The invention provides a method for producing purified compositions of bispecific molecules each comprising (a) an antigen recognition portion that binds a C3b-like receptor and (b) one or more double-stranded DNA molecules cross-linked to the antigen recognition portion. In particular, the invention provides a method for purifying bispecific molecules using alcohol precipitation. The invention also relates to the purified products of bispecific molecules. The purified compositions of the invention are useful for treating Systemic Lupus Erythematosus (SLE).
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申请公布号 |
US2006147457(A1) |
申请公布日期 |
2006.07.06 |
申请号 |
US20030514547 |
申请日期 |
2003.05.13 |
申请人 |
PORTER JAMES P;EBELLE RENAY A;CASEY LESLIE;LUKACHER NADYA |
发明人 |
PORTER JAMES P.;EBELLE RENAY A.;CASEY LESLIE;LUKACHER NADYA |
分类号 |
A61K39/395;A61K31/7088;A61K47/48;C07H21/02;C07K16/28;C07K16/44 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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