PROCESS FOR THE PREPARATION OF CHIRAL AMINES

摘要

The invention relates to a process for the preparation of a chiral amine, whereby a ketone or aldehyde is contacted with an enantiomerically enriched phenylglycine amide to give an imine, whereby the imine is subsequently contacted with a Reformatsky reagent and the formed compound is subsequently converted into a chiral amine by means of hydrogenolysis, oxidation or a retro Strecker method.