GENERATION OF VIRUS-LIKE PARTICLES AND USE AS PANFILOVIRUS VACCINE
摘要
In this application are described filoviruslike particles for both Ebola and Marburg and their use as a diagnostic and therapeutic agent as well as a filovirus vaccine. Also described are the association of Ebola and Marburg with lipid rafts during assembly and budding, and the requirement of functional rafts for entry of filoviruses into cells.
申请公布号
WO2006046963(A9)
申请公布日期
2006.07.06
申请号
WO2005US12378
申请日期
2005.04.13
申请人
U.S. ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUSDISEASES;BAVARI, SINA;AMAN, M., JAVAD;WARFIELD, KELLY