发明名称 Mglu receptors antagonists for treating disorders associated with mglu receptors including addiction and depression
摘要 Methods are provided for treating disorders associated with mGlu receptors by simultaneously inhibiting at least two mGIuRs belonging to at least two different groups. In one embodiment, there are provided methods for treating a disorder associated with MGlu receptors 2, 3, and 5, including administering to a subject in need thereof an effective amount of at least one antagonist which modulates mGIuR2, mGIuR3, and mGIuRS. The disorders treated by the method include, for example, nicotine addiction, cocaine addiction, and depression.
申请公布号 US2006148835(A1) 申请公布日期 2006.07.06
申请号 US20050527525 申请日期 2005.10.14
申请人 MARKOU ATHINA;KENNY PAUL;PATERSON NEIL;SEMENOVA SVETLANA 发明人 MARKOU ATHINA;KENNY PAUL;PATERSON NEIL;SEMENOVA SVETLANA
分类号 A61K31/44;A61K31/352;A61P25/24;A61P25/30 主分类号 A61K31/44
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