摘要 |
<p>The invention relates to compounds of the formula (I) in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases such as inflammatory diseases.</p> |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH;KNIEPS, STEPHANIE;DEDIO, JUERGEN;HEITSCH, HOLGER;CZECHTIZKY, WERNGARD;GRUENEBERG, SVEN;SHIMSHOCK, STEPHEN;KOSLEY, RAYMOND, W.;LANTER, CAROLINA;LI, HUI;SHER, ROSY;WEICHSEL, ALEKSANDRA |
发明人 |
KNIEPS, STEPHANIE;DEDIO, JUERGEN;HEITSCH, HOLGER;CZECHTIZKY, WERNGARD;GRUENEBERG, SVEN;SHIMSHOCK, STEPHEN;KOSLEY, RAYMOND, W.;LANTER, CAROLINA;LI, HUI;SHER, ROSY;WEICHSEL, ALEKSANDRA |