Fused bicyclic carboxamide derivates for use as CXCR2 inhibitors in the treatment of inflammation

摘要

The invention relates to compounds of the formula I
in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and the pharmaceutically acceptable salts thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts thereof are suitable for the prevention and treatment of chemokine mediated diseases such as inflammation.