发明名称 HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
摘要 The application is directed to haloalkyl- substituted compounds of formula (I) wherein R7 represents haloalkyl; and R1, R2, R3, R4, R 5, R6 and R8 are as defined in the claims. The compounds are inhibitors of cysteine proteases, in particular cathepsins B, K, L, F and S and are therefore useful in treating diseases mediated by these proteases. Pharmaceutical compositions containing these compounds and their use are also disclosed.
申请公布号 KR20060079143(A) 申请公布日期 2006.07.05
申请号 KR20057022300 申请日期 2005.11.22
申请人 AXYS PHARMACEUTICALS, INC. 发明人 LINK JOHN O.;MOSSMAN CRAIG J.;WOO SOON H.;ZIPFEL SHEILA M.
分类号 C07C255/46;C07C317/48;C07C323/60;C07D211/66;C07D213/32;C07D231/12;C07D241/12;C07D277/30;C07D309/14;C07D333/20;C07D335/02 主分类号 C07C255/46
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