发明名称 Synthesis of optically active cyclohexylphenylglycolate esters
摘要 <p>A process for the preparation of optically active cyclohexylglycolate esters is described. The process utilizes carboxylic acid activation to couple (R)- or (S)-cyclohexylphenylglycolic acid (CHPGA) with 4-N,N-diethylamino butynol or other propargyl alcohol derivatives. The preparation of the hydrochloride salt is also described.</p>
申请公布号 EP1424321(B1) 申请公布日期 2006.07.05
申请号 EP20030104950 申请日期 1999.10.22
申请人 SEPRACOR INC 发明人 BAKALE, ROGER, P.;LOPEZ, JORGE, L;MCCONVILLE, FRANCIS, X;VANDENBOSSCHE, CHARLES, P;SENANAYAKE, CHRIS, HUGH
分类号 C07C51/487;C07B57/00;C07C51/43;C07C59/11;C07C59/54;C07C67/12;C07C69/732;C07C69/96;C07C213/06;C07C219/20;C07C229/36 主分类号 C07C51/487
代理机构 代理人
主权项
地址