PROCESS FOR PRODUCING AMINOPYRROLIDINE DERIVATIVE AND INTERMEDIATE COMPOUND

摘要

There is provided an industrial production method of an aminopyrrolidine derivative having chemokine receptor antagonist activity represented by the following formula, a synthetic intermediate thereof and a production method thereof:
wherein R 11 is H, C 1 -C 6 alkyl or C 2 -C 7 alkanoyl; R 12 , R 14 , R 15 , R 16 and R 17 are H, halogen, optionally halogenated C 1 -C 6 alkyl, optionally halogenated C 1 -C 6 alkoxy, hydroxyl or C 2 -C 7 alkoxycarbonyl; R 23 , R 24 , R 25 and R 26 are H, halogen, optionally halogenated C 1 -C 6 alkyl, optionally halogenated C 1 -C 6 alkoxy or hydroxyl; and R 3 is H or C 1 -C 6 alkyl.