| 发明名称 |
Glycosyl sulfotransferases GST-4alpha, GST-4beta, and GST-6 |
| 摘要 |
Novel glycosylsulfotransferases (GST-4alpha, GST-4beta, and GST-6) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including various diagnostic and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of GST-4alpha, GST-4beta, and GST-6.
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| 申请公布号 |
US7070971(B2) |
申请公布日期 |
2006.07.04 |
| 申请号 |
US20030697828 |
申请日期 |
2003.10.29 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ROSEN STEVEN;LEE JIN KYU;HEMMERICH STEFAN |
| 分类号 |
A01K67/027;C12N9/10;A61K31/7125;A61K35/76;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P1/00;A61P1/16;A61P3/10;A61P5/38;A61P7/06;A61P9/00;A61P9/10;A61P11/06;A61P11/16;A61P13/12;A61P17/00;A61P17/06;A61P21/00;A61P21/04;A61P27/02;A61P27/16;A61P29/00;A61P31/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K1/00;C07K16/40;C12N1/15;C12N1/19;C12N1/20;C12N1/21;C12N5/10;C12N15/00;C12N15/09;C12P21/08;C12Q1/48;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
A01K67/027 |
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