发明名称 |
Retroviral vectors with foreign-sequence insertion between retroviral primer binding site and retroviral splice donor |
摘要 |
The subject of the invention is retroviral gene transfer vectors in which foreign sequences are introduced between the retroviral primer binding site (PBS) and the retroviral splice donor (SD). The efficiency of gene expression is improved by this modification, and the vectors are characterized by an increased reliability during use.
|
申请公布号 |
US7070992(B2) |
申请公布日期 |
2006.07.04 |
申请号 |
US20010953572 |
申请日期 |
2001.09.10 |
申请人 |
HEINRICH-PETTE-INSTITUTE |
发明人 |
BAUM CHRISTOPHER;SCHAUMANN DANIEL |
分类号 |
C12N1/00;C12N15/09;A61K35/76;A61K48/00;C07K14/15;C12N5/10;C12N7/00;C12N7/01;C12N15/63;C12N15/70;C12N15/74;C12N15/867;C12P21/02 |
主分类号 |
C12N1/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|