发明名称 |
PHARMACEUTICAL COMPOSITIONS OF AMLODIPINE AND ATORVASTATIN |
摘要 |
A pharmaceutical composition comprising two components: (a) one component comprising a granulation of atorvastatin or pharmaceutically acceptable salts thereof and a carrier including an alkalizing agent that forms a pH greater than 5; and (b) a second component comprising amlodipine or pharmaceutically acceptable salts thereof and a carrier excluding an alkalizing agent that forms a pH greater than 5, wherein the two components are combined to form a final composition for a solid dosage form is described as well as methods to prepare the compositions, kits for containing such compositions, and a method of treating angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and/or hypercholesterolemia, and symptoms of cardiac risk using a therapeutically effective amount of the pharmaceutical composition. |
申请公布号 |
EA006998(B1) |
申请公布日期 |
2006.06.30 |
申请号 |
EA20040000028 |
申请日期 |
2002.07.29 |
申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
ALANI LAMAN;KHAN SADATH, ULLA;MACNEIL THOMAS, MICHAEL;MUHAMMAD NOUMAN, ABDUL-HUSSAIN |
分类号 |
A61J3/06;A61K31/40;A61K9/16;A61K9/20;A61K31/401;A61K31/44;A61K31/4422;A61K47/02;A61K47/04;A61P3/06;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P9/14;A61P43/00 |
主分类号 |
A61J3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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