摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for preparing an alpha lipoic acid/cyclodextrin complex rapidly and easily even at room temperature free from faults of conventional technique. <P>SOLUTION: The invention relates to the process for preparation of the cyclodextrin/alpha lipoic acid complex characterized in that, in a first step of a two step process, the alpha lipoic acid and the cyclodextrin are dissolved in an aqueous alkaline solution having a pH above pH 7, and in a second step, an acid is added to lower the pH of the solution to a pH below pH 7. <P>COPYRIGHT: (C)2006,JPO&NCIPI |