发明名称 Benzimidazole compounds and antiviral uses thereof
摘要 The present invention relates to novel benzimidazole compounds that have useful antiviral activity. More specifically, the invention encompasses benzimidazole compounds that inhibit membrane fusion associated events such as viral transmission, reduce viral load or otherwise treat viral infections. The invention also encompasses the use of benzimidazole compounds as inhibitors of membrane fusion associated events, such as viral transmission. In another embodiment, the invention encompasses processes for making benzimidazole compounds, methods of using the benzimidazole compounds and compositions comprising the benzimidazole compounds. Finally, the invention provides methods for treating, preventing or ameliorating symptoms associated with respiratory infection, particularly that caused by Respiratory Syncytial Virus utilizing the novel benzimidazole compounds of the invention.
申请公布号 US2006142365(A1) 申请公布日期 2006.06.29
申请号 US20060346758 申请日期 2006.02.02
申请人 TRIMERIS, INC. 发明人 LACKEY JOHN W.;KINDER DANIEL S.;TVERMOES NICOLAI A.
分类号 A61K31/4184;C07D235/10;C07D235/12;C07D235/14;C07D401/06;C07D401/14;C07D403/02;C07D403/14;C07D405/06;C07D405/14;C07D409/14;C07D413/06;C07D413/14;C07D417/06;C07D417/14;C07D521/00;C07F9/6506;C07F9/6558 主分类号 A61K31/4184
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