A FIBRINOLYSIN OF AGKISTRODON ACUTUS VENOM AND ITS USAGE
摘要
<p>The present invention disclosed a fibrinolysin gene of Agkistrodon acutus, a vector containing the said gene and the host cell which transformed by the vector. The fibrinolysin could be used in treating diseases caused by thrombus. The fibrinolysin FII is purified from the crude venom of Agkistrodon acutus, and the corresponding gene is cloned. It is recommended to produce the fibrionolysin by the yeast expression system. The activity of the fibrionlysin is also determined. The advantages of this invention are hat the expression level and activity of the fibrinolysin are both high and the quality of he fibrinolysin is stable.</p>
申请公布号
WO2006066441(A1)
申请公布日期
2006.06.29
申请号
WO2004CN01466
申请日期
2004.12.20
申请人
SUN YAT-SEN UNIVERSITY;YAN, GUANGMEI;CHEN, JIASHU;QIU, PENGXIN;SHAN, HONG
发明人
YAN, GUANGMEI;CHEN, JIASHU;QIU, PENGXIN;SHAN, HONG