CHEMICAL COMPOUNDS

摘要

Compounds of formula (I): wherein: when X is NR<SUP>5</SUP>, Y is absent or is CH<SUB>2</SUB>; when X is CH<SUB>2</SUB>, Y is absent, CH<SUB>2</SUB>, NR<SUP>6</SUP>, O, S, S(O) or S(O)<SUB>2</SUB>; Z is a 5- or 6-membered heterocyclyl ring; compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating CCR5 receptor activity in a warm blooded animal).