发明名称 |
Synthesis of 2-alkyl amino acids |
摘要 |
A method of preparing a 2-alkyl amino acid involves the aziridination of an alkylacrylate and the opening of the aziridine ring by addition of a side chain. This method can result in the preparation of enantiomeric excess of a 2-alkyl amino acid. The invention also discloses a method of preparing a class of iron chelating agents related to desferrithiocin, all of which contain a thiazoline ring. In this method, an aryl nitrile or imidate is condensed with cysteine, a 2-alkyl cysteine, or a cysteine ester.
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申请公布号 |
US2006142586(A1) |
申请公布日期 |
2006.06.29 |
申请号 |
US20050287891 |
申请日期 |
2005.11.28 |
申请人 |
CHORGHADE MUKUND S;GURJAR MUKUND K;CHANDA BHANU M |
发明人 |
CHORGHADE MUKUND S.;GURJAR MUKUND K.;CHANDA BHANU M. |
分类号 |
C07D233/64;C07D277/56;A61K31/426;A61P7/02;A61P11/06;A61P29/00;A61P31/12;C07B53/00;C07B55/00;C07B61/00;C07C217/46;C07C227/18;C07C229/06;C07C229/42;C07C249/02;C07C253/00;C07C255/53;C07C255/54;C07C257/08;C07C319/02;C07C319/06;C07C319/12;C07C319/20;C07C323/00;C07C323/25;C07C323/35;C07C323/52;C07C323/56;C07C323/58;C07D203/04;C07D213/55;C07D233/16;C07D237/02;C07D277/04;C07D277/08;C07D277/12;C07D277/14;C07D277/18;C07D303/24 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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