发明名称 Hydroxyamidine and hydroxyguanidine compounds as urokinase inhibitors
摘要 The present invention relates to novel compounds for inhibiting the urokinase plasminogen activator (uPA), which have high bioavailability and oral administerability, and also to the use thereof as therapeutic active compounds for the treatment of urokinase- or/and urokinase receptor-associated disorders such as, for example, tumors and metastasizing. The invention relates in particular to compounds containing hydroxyamidine or hydroxyguanidine groups.
申请公布号 US2006142305(A1) 申请公布日期 2006.06.29
申请号 US20050287480 申请日期 2005.11.28
申请人 WILEX AG 发明人 SPERL STEFAN;BUERGLE MARKUS;SCHMALIX WOLFGANG;WOSIKOWSKI KATJA;CLEMENT BERND
分类号 A61K31/495;A61P35/00;C07D295/185;C07K5/06;C07K5/065 主分类号 A61K31/495
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