摘要 |
Compounds and methods of using these compounds to treat neurodegenerative diseases, especially Alzheimer's disease, are provided. The compounds that are provided for the treatment of neurodegenerative diseases can be represented by a general formula (I): wherein R<SUB>1 </SUB>is Me, Et or PhCH<SUB>2</SUB>; R<SUB>2 </SUB>is H, PhCH<SUB>2 </SUB>or 6-Me-3-Py-(CH<SUB>2</SUB>)<SUB>2</SUB>; and R<SUB>3 </SUB>is H, Me or Br. The solid line accompanied by the dotted line <img id="custom-character-00001" he="2.79mm" wi="6.35mm" file="US20060140866A1-20060629-P00001.TIF" alt="custom character" img-content="character" img-format="tif"/> i.e. represents a single or double bond and salts thereof with pharmacologically acceptable acids and quaternary derivatives.
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