| 发明名称 |
N-sulfonylpiperidines as metalloproteinase inhibitors (tace) |
| 摘要 |
Compounds of formula (1), wherein Z is -CONR<SUB>15</SUB>OH or -N(OH)CHO and X is -(CR<SUB>9</SUB>R<SUB>10</SUB>)t-Q-(CR<SUB>11</SUB>R<SUB>12</SUB>)u- (where t and u are independently 0 or 1 with the proviso that t and u cannot both be 0);are inhibitors of metalloproteinases and in particular TACE.
|
| 申请公布号 |
US2006142336(A1) |
申请公布日期 |
2006.06.29 |
| 申请号 |
US20050521042 |
申请日期 |
2005.12.07 |
| 申请人 |
BURROWS JEREMY N;TUCKER HOWARD |
发明人 |
BURROWS JEREMY N.;TUCKER HOWARD |
| 分类号 |
A61K31/4545;C07D211/22;A61K31/445;A61K31/4709;A61K31/506;A61P9/00;A61P19/02;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D211/44;C07D211/68;C07D211/96;C07D401/02;C07D401/12;C07D401/14 |
主分类号 |
A61K31/4545 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
