| 摘要 |
A medicament source (1) has a container (2) and a crimped closure (3). The closure sealingly holds to the container a metered-dose release valve, of which the spout (4) only is visible externally. The container has a neck (5) and a protruding rim (6) at which the crimp locates. The container is of moulded polymer (7) and has an outer, perforate sleeve (8) of aluminium, providing mechanical strength for pressure retention. The neck has a relatively thicker wall thickness and the end (9) is domed inwards, both for pressure retention. The polymer is of three layers or laminations. The innermost layer (11) is of polytetrafluoroethylene (PTFE) material to provide an inert layer with which the medicament and its propellant will not react or combine in any way. The middle polymer layer is of nylon material to provide a propellant tight layer (12), to contain the propellant, whose molecules may be able to pass through the PTFE layer. The outer polymer layer (14) is of polypropylene (PP) to provide both water tightness and mechanical integrity of the container. |
