发明名称 |
FUSION PROTEINS AND METHODS FOR DETERMINING PROTEIN-PROTEIN-INTERACTIONS IN LIVING CELLS AND CELL LYSATES, NUCLEIC ACIDS ENCODING THESE FUSION PROTEINS, AS WELL AS VECTORS AND KITS CONTAINING THESE |
摘要 |
<p>The present invention refers to inventive fusion proteins, to a method for detecting protein-protein-interactions in living cells and cell lysates using these inventive fusion proteins. The present invention also refers to a screening method for identifying compounds suitable to modify, i.e. inhibit or enhance, protein-protein-interaction using these fusion porteins. Additionally a method for detecting cells is disclosed comprising an unknown protein that interacts with a known protein. Along with the inventive fusion proteins used for these methods encoding nucleic acids, corresponding vectors and host cells transfected accordingly are disclosed herewith.</p> |
申请公布号 |
WO2006066959(A1) |
申请公布日期 |
2006.06.29 |
申请号 |
WO2005EP13960 |
申请日期 |
2005.12.22 |
申请人 |
BH GSF-FORSCHUNGSZENTRUM FUER UMWELT UND GESUNDHEIT GM;WOLFF, HORST;BREBECK, ANDREA;ZIEGLER, MANJA;BRACK-WERNER, RUTH |
发明人 |
WOLFF, HORST;BREBECK, ANDREA;ZIEGLER, MANJA;BRACK-WERNER, RUTH |
分类号 |
C07K14/47;C12N15/00;G01N33/58;G01N33/68 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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