发明名称 COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY
摘要 The present invention relates to compounds that interact with ion channels. In particular, the invention relates to compounds having the structural Formula (I), (II), (III) or (IV), stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or a pharmaceutically acceptable salt and/or solvate thereof, Formula (I), (II), (III), (IV), wherein X<SUP>1</SUP>, X<SUP>2</SUP>, Y, Z, W, R<SUP>1</SUP>, R<SUP>8</SUP> , R<SUP>9</SUP>, R<SUP>10</SUP>, L, A, z, and n have the meaning defined in claim 1. The invention also relates to methods for preparing said compounds, to pharmaceutical compositions comprising said compounds, and to the use of said compounds in methods for treatment of the human and animal body.
申请公布号 WO2006066879(A2) 申请公布日期 2006.06.29
申请号 WO2005EP13715 申请日期 2005.12.20
申请人 DEVGEN N.V.;BLOM, PETRA;DE KERPEL, JAN, OCTAAF;FOURMAINTRAUX, ERIC, PIERRE, PAUL, RENE;KALETTA, TITUS, JAN;LEYSEN, DIRK 发明人 BLOM, PETRA;DE KERPEL, JAN, OCTAAF;FOURMAINTRAUX, ERIC, PIERRE, PAUL, RENE;KALETTA, TITUS, JAN;LEYSEN, DIRK
分类号 C07D307/85;A61K31/343;A61K31/404;A61P9/00;C07D209/42;C07D215/48;C07D307/82;C07D333/70;C07D401/04;C07D401/06;C07D401/12;C07D409/12 主分类号 C07D307/85
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