发明名称 |
COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY |
摘要 |
The present invention relates to compounds that interact with ion channels. In particular, the invention relates to compounds having the structural Formula (I), (II), (III) or (IV), stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or a pharmaceutically acceptable salt and/or solvate thereof, Formula (I), (II), (III), (IV), wherein X<SUP>1</SUP>, X<SUP>2</SUP>, Y, Z, W, R<SUP>1</SUP>, R<SUP>8</SUP> , R<SUP>9</SUP>, R<SUP>10</SUP>, L, A, z, and n have the meaning defined in claim 1. The invention also relates to methods for preparing said compounds, to pharmaceutical compositions comprising said compounds, and to the use of said compounds in methods for treatment of the human and animal body. |
申请公布号 |
WO2006066879(A2) |
申请公布日期 |
2006.06.29 |
申请号 |
WO2005EP13715 |
申请日期 |
2005.12.20 |
申请人 |
DEVGEN N.V.;BLOM, PETRA;DE KERPEL, JAN, OCTAAF;FOURMAINTRAUX, ERIC, PIERRE, PAUL, RENE;KALETTA, TITUS, JAN;LEYSEN, DIRK |
发明人 |
BLOM, PETRA;DE KERPEL, JAN, OCTAAF;FOURMAINTRAUX, ERIC, PIERRE, PAUL, RENE;KALETTA, TITUS, JAN;LEYSEN, DIRK |
分类号 |
C07D307/85;A61K31/343;A61K31/404;A61P9/00;C07D209/42;C07D215/48;C07D307/82;C07D333/70;C07D401/04;C07D401/06;C07D401/12;C07D409/12 |
主分类号 |
C07D307/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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