发明名称 THE COMBINATION OF AN ANTIPSYCHOTIC AND A GLYCINE TRANSPORTER TYPE I INHIBITOR FOR THE TREATMENT OF SCHIZOPHRENIA
摘要 The present invention relates to the combination of an antipsychotic agent selected from D2 receptor antagonists, partial agonists, or inverse agonists, and a glycine transporter type 1 (GlyT-1) inhibitor. Accordingly, the present invention relates to the treatment of patients with schizophrenia, in particular treatment of patients with positive symptoms and negative symptoms, and cognitive impairment in patients with schizophrenia.
申请公布号 WO2006000222(A3) 申请公布日期 2006.06.29
申请号 WO2005DK00422 申请日期 2005.06.23
申请人 H. LUNDBECK A/S;JOERGENSEN, STEFFEN, WAD;DAHL, ALLAN, CARSTEN;DIDRIKSEN, MICHAEL;LARSEN, FRANK;WAERNER, TORBJOERN;SOEBY, KARINA, KROEJER;TOFT, DORTHE, BACH;HELBOE, THOMAS 发明人 JOERGENSEN, STEFFEN, WAD;DAHL, ALLAN, CARSTEN;DIDRIKSEN, MICHAEL;LARSEN, FRANK;WAERNER, TORBJOERN;SOEBY, KARINA, KROEJER;TOFT, DORTHE, BACH;HELBOE, THOMAS
分类号 A61K45/06;A61K31/495;A61P25/18 主分类号 A61K45/06
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