It is intended to provide a host microorganism capable of increasing productivity of a protein or a polypeptide; a recombinant microorganism obtained by introducing a gene encoding a protein or a polypeptide into the host microorganism; and a process for producing a protein or a polypeptide using the recombinant microorganism. The recombinant microorganism is prepared by using a microorganism, in which aprX gene of Bacillus subtilis or a gene corresponding to the gene has been deleted or inactivated, as a host and introducing a gene encoding a heterologous protein or polypeptide into the host. The recombinant microorganism is used in the process for producing a protein or a polypeptide.
申请公布号
WO2006068148(A1)
申请公布日期
2006.06.29
申请号
WO2005JP23390
申请日期
2005.12.20
申请人
KAO CORPORATION;SHINSHU UNIVERSITY;KODAMA, TAKEKO;ENDO, KEIJI;OZAKI, KATSUYA;SEKIGUCHI, JUNICHI