| 摘要 |
<p>The present invention provides compounds of formula (I), wherein both p's are one or two, R<SUP>1</SUP> is generally heteroaryl or cycloalkyl, R<SUP>2</SUP> is C<SUB>3-6</SUB>cycloalkyl or phenyl and R<SUP>3</SUP> is heteroaryl, and pharmaceutically acceptable salts thereof, as GlyT1 inhibitors for treating schizophrenia, pharmaceutical compositions comprising the same and methods for their preparation.</p> |
| 申请人 |
MERCK SHARP & DOHME LIMITED;BLACKABY, WESLEY, PETER;FLETCHER, STEPHEN, ROBERT;JENNINGS, ANDREW;LEWIS, RICHARD, THOMAS;NAYLOR, ELIZABETH, MARY;STREET, LESLIE, JOSEPH;THOMSON, JOANNE |
发明人 |
BLACKABY, WESLEY, PETER;FLETCHER, STEPHEN, ROBERT;JENNINGS, ANDREW;LEWIS, RICHARD, THOMAS;NAYLOR, ELIZABETH, MARY;STREET, LESLIE, JOSEPH;THOMSON, JOANNE |
