发明名称 3-Alkanolamino-propionic acid derivatives used as inhibitors of integrin AvB6
摘要 Novel biphenyl derivatives of the general formula I in which R<SUB>1</SUB>, R<SUB>1', R</SUB><SUB>1''</SUB>, R<SUB>2</SUB>, R<SUB>2'</SUB>, R3 and n are as defined in Patent claim 1 , stereoisomers thereof and physiologically acceptable salts or solvates thereof are novel integrin inhibitors which preferentially inhibit the alphavbeta6 integrin receptor. The novel compounds can be used, in particular, as medicaments.
申请公布号 ZA200407035(B) 申请公布日期 2006.06.28
申请号 ZA20040007035 申请日期 2004.10.02
申请人 MERCK PATENT GMBH 发明人 WOLFGANG STAEHLE;ALFRED JONCZYK;OLIVER SCHADT;SIMON GOODMAN
分类号 A61K;A61K31/44;A61K31/4402;A61P;A61P1/04;A61P1/18;A61P3/14;A61P7/02;A61P9/00;A61P9/10;A61P11/00;A61P13/02;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;C07D;C07D213/74 主分类号 A61K
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