| 摘要 |
The present invention relates to a prophylactic or therapeutic agent against a disease or pathological condition caused by angiogenesis, comprising, as an active ingredient, a cyclic amine compound represented by the general formula (1):
wherein R 1 , R 2 , and R 3 each independently represent a hydrogen atom, a halogen atom, a hydroxy group, an alkyl group, a halogen-substituted alkyl group, an alkoxy group, an alkylthio group, a carboxyl group, an alkoxycarbonyl group, or an alkanoyl group; W 1 and W 2 each independently represent N or CH; X represents O, NR 4 , CONR 4 , -or NR 9 -CO; R 4 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted heteroaralkyl group; and l, m, and n each represent a number of 0 or 1, or a salt thereof, or a solvate thereof.
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