发明名称 Process for the preparation of a powder containing glucopyranosyl-alditols cristalline particules
摘要 Preparation of a powder (I) containing crystalline particles of glucopyranosyl-alditols (A), comprises mixture of glucopyranosyl-alditols syrup (II) and (A), on the basis of dry matter, where the mixture is made by simultaneously dispersing (II) and (A) in an open rotary container containing granules of glucopyranosyl-alditols base (III), and recuperation of (III) from the container and the crystallization of (A) contained in the granules. Preparation of a powder (I) containing crystalline particles of glucopyranosyl-alditols (A), comprises mixture of glucopyranosyl-alditols syrup (II) having a content of dry matter (8 wt.%) and a content of (A) is 95 (preferably 98) wt.%, on the basis of dry matter, where the mixture is made by simultaneously dispersing (II) and the particles containing (A) in an open rotary container containing granules of glucopyranosyl-alditols base (III), by means of which (II) and the particles containing (A) are mixed on the surface of granules of (III) in the container, recuperation of granules of (III) from the container and crystallization of (A) contained in the granules (where the granules of (II) in the container being maintained in movement by the rotation of the container). Independent claims are included for: (1) (I) containing crystalline particles of (A) which is obtained by the above process; and (2) preparations of tablet and confectioneries using (I) containing crystalline particles of (A).
申请公布号 EP1674475(A1) 申请公布日期 2006.06.28
申请号 EP20050292670 申请日期 2005.12.14
申请人 ROQUETTE FRERES 发明人 DUFLOT, PIERRICK;ZHOU, LIUMING
分类号 C07H15/04;A23L1/09;A61K38/43 主分类号 C07H15/04
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