| 摘要 |
An anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPR0140-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprising the expression product of either a plasmid designated pVgl:HuPR0140 HG2-VH (ATCC Deposit Designation PTA-4098) or a plasmid designated pVgl:HuPRO140 (mut B+D+I)-VH (ATCC Deposit Designation PTA-4099), or a fragment of such antibody, which binds to CCR5 on the surface of a human cell. |
| 申请人 |
PROGENICS PHARMACEUTICALS, INC.;PROTEIN DESIGN LABS, INC. |
发明人 |
OLSON, WILLIAM, C.;MADDON, PAUL, J.;NAOYA TSURUSHITA;HINTON, PAUL, R.;MAXIMILLANO VASQUEZ |
